rfwd3 protein (Esox lucius) - STRING interaction network

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gene neighborhood

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protein homology

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[Homology]

Score

rfwd3

Ring finger and WD repeat domain 3. (741 aa)

Predicted Functional Partners:

rpa3

0.956

primpol

0.922

rpa1

0.900

LOC105028498

0.900

meiob

0.736

wrn

0.721

smarcal1

0.694

LOC105017803

0.626

rpa2

0.626

ENSELUP00000025641

0.626

Your Current Organism:

Esox lucius

NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSELUP00000025641	LOC105017803	ENSELUP00000025641	ENSELUP00000013602	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	0.901
ENSELUP00000025641	LOC105028498	ENSELUP00000025641	ENSELUP00000029262	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.925
ENSELUP00000025641	meiob	ENSELUP00000025641	ENSELUP00000019359	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Methionine sulfoxide reductase B1b.	0.813
ENSELUP00000025641	primpol	ENSELUP00000025641	ENSELUP00000028331	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Primase and polymerase (DNA-directed).	0.638
ENSELUP00000025641	rfwd3	ENSELUP00000025641	ENSELUP00000029957	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Ring finger and WD repeat domain 3.	0.626
ENSELUP00000025641	rpa1	ENSELUP00000025641	ENSELUP00000022084	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.925
ENSELUP00000025641	rpa3	ENSELUP00000025641	ENSELUP00000042114	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Uncharacterized protein.	0.954
ENSELUP00000025641	smarcal1	ENSELUP00000025641	ENSELUP00000009921	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Uncharacterized protein; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.	0.736
ENSELUP00000025641	wrn	ENSELUP00000025641	ENSELUP00000038002	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	WRN RecQ like helicase.	0.978
LOC105017803	ENSELUP00000025641	ENSELUP00000013602	ENSELUP00000025641	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	0.901
LOC105017803	LOC105028498	ENSELUP00000013602	ENSELUP00000029262	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.925
LOC105017803	meiob	ENSELUP00000013602	ENSELUP00000019359	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Methionine sulfoxide reductase B1b.	0.813
LOC105017803	primpol	ENSELUP00000013602	ENSELUP00000028331	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Primase and polymerase (DNA-directed).	0.638
LOC105017803	rfwd3	ENSELUP00000013602	ENSELUP00000029957	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Ring finger and WD repeat domain 3.	0.626
LOC105017803	rpa1	ENSELUP00000013602	ENSELUP00000022084	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.925
LOC105017803	rpa3	ENSELUP00000013602	ENSELUP00000042114	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Uncharacterized protein.	0.954
LOC105017803	smarcal1	ENSELUP00000013602	ENSELUP00000009921	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Uncharacterized protein; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.	0.736
LOC105017803	wrn	ENSELUP00000013602	ENSELUP00000038002	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	WRN RecQ like helicase.	0.978
LOC105028498	ENSELUP00000025641	ENSELUP00000029262	ENSELUP00000025641	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	0.925
LOC105028498	LOC105017803	ENSELUP00000029262	ENSELUP00000013602	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	0.925