node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LOC105012654 | LOC105015131 | ENSELUP00000014484 | ENSELUP00000030181 | Cytochrome P450, family 51; Belongs to the cytochrome P450 family. | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 0.868 |
LOC105012654 | LOC105021720 | ENSELUP00000014484 | ENSELUP00000017449 | Cytochrome P450, family 51; Belongs to the cytochrome P450 family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.966 |
LOC105012654 | hmgcr | ENSELUP00000014484 | ENSELUP00000005670 | Cytochrome P450, family 51; Belongs to the cytochrome P450 family. | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 0.891 |
LOC105012654 | insig1 | ENSELUP00000014484 | ENSELUP00000004960 | Cytochrome P450, family 51; Belongs to the cytochrome P450 family. | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. | 0.553 |
LOC105012654 | insig2 | ENSELUP00000014484 | ENSELUP00000029943 | Cytochrome P450, family 51; Belongs to the cytochrome P450 family. | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. | 0.553 |
LOC105012654 | mvk | ENSELUP00000014484 | ENSELUP00000001628 | Cytochrome P450, family 51; Belongs to the cytochrome P450 family. | Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. | 0.657 |
LOC105012654 | sqle | ENSELUP00000014484 | ENSELUP00000028878 | Cytochrome P450, family 51; Belongs to the cytochrome P450 family. | Squalene epoxidase a. | 0.979 |
LOC105015131 | LOC105012654 | ENSELUP00000030181 | ENSELUP00000014484 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | Cytochrome P450, family 51; Belongs to the cytochrome P450 family. | 0.868 |
LOC105015131 | LOC105021720 | ENSELUP00000030181 | ENSELUP00000017449 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.999 |
LOC105015131 | hmgcl | ENSELUP00000030181 | ENSELUP00000001681 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 3-hydroxy-3-methylglutaryl-CoA lyase. | 0.794 |
LOC105015131 | hmgcll1 | ENSELUP00000030181 | ENSELUP00000021085 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1. | 0.772 |
LOC105015131 | hmgcr | ENSELUP00000030181 | ENSELUP00000005670 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 0.901 |
LOC105015131 | insig1 | ENSELUP00000030181 | ENSELUP00000004960 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. | 0.757 |
LOC105015131 | insig2 | ENSELUP00000030181 | ENSELUP00000029943 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. | 0.757 |
LOC105015131 | mvk | ENSELUP00000030181 | ENSELUP00000001628 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. | 0.994 |
LOC105015131 | sqle | ENSELUP00000030181 | ENSELUP00000028878 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | Squalene epoxidase a. | 0.872 |
LOC105015131 | ubiad1 | ENSELUP00000030181 | ENSELUP00000016812 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | UbiA prenyltransferase domain containing 1. | 0.835 |
LOC105021720 | LOC105012654 | ENSELUP00000017449 | ENSELUP00000014484 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Cytochrome P450, family 51; Belongs to the cytochrome P450 family. | 0.966 |
LOC105021720 | LOC105015131 | ENSELUP00000017449 | ENSELUP00000030181 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 0.999 |
LOC105021720 | hmgcl | ENSELUP00000017449 | ENSELUP00000001681 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 3-hydroxy-3-methylglutaryl-CoA lyase. | 0.992 |