STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SH2B2SH2B adaptor protein 2. (709 aa)    
Predicted Functional Partners:
LOC105005877
Tyrosine-protein kinase receptor.
    
 0.953
CBL
Cbl proto-oncogene.
    
 0.952
cbl
Cbl proto-oncogene, E3 ubiquitin protein ligase.
    
 0.952
cblb
Cbl proto-oncogene B, E3 ubiquitin protein ligase.
    
 0.952
LOC105013161
Growth factor receptor bound protein 2.
    
 0.603
LOC105012273
Growth factor receptor-bound protein 2a.
    
 0.603
LOC105024705
Tyrosine-protein kinase.
    
 0.601
jak2
Tyrosine-protein kinase.
    
 0.601
LOC105014676
Tyrosine-protein kinase.
    
 0.601
jak1
Tyrosine-protein kinase.
    
 0.601
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.