STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
asipAgouti signaling protein 1. (123 aa)    
Predicted Functional Partners:
Mc1r
Melanocyte-stimulating hormone receptor.
     
 0.965
srp14
Signal recognition particle 14.
      
 0.613
pomc
Proopiomelanocortin.
      
 0.590
agrp
Agouti domain-containing protein.
      
 0.587
LOC105017441
SET domain and mariner transposase fusion gene.
      
 0.586
oca2
Oculocutaneous albinism II.
      
 0.557
slc24a5
Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
      
 0.553
ENSELUP00000035291
Uncharacterized protein.
      
 0.514
tyr
Tyrosinase.
      
 0.481
ahcy
Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family.
      
 0.461
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.