STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSELUP00000038195Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (189 aa)    
Predicted Functional Partners:
LOC105013575
Tyrosine-protein kinase.
   
 0.920
cav2
Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.
  
0.896
itgb5
Integrin beta; Belongs to the integrin beta chain family.
     
 0.696
LOC105006835
Integrin beta; Belongs to the integrin beta chain family.
     
 0.696
LOC105017152
Integrin beta; Belongs to the integrin beta chain family.
     
 0.696
LOC105013321
Integrin beta; Belongs to the integrin beta chain family.
     
 0.696
itgb6
Integrin beta; Belongs to the integrin beta chain family.
     
 0.696
LOC105019428
Integrin beta; Belongs to the integrin beta chain family.
     
 0.696
LOC105017753
Integrin beta; Belongs to the integrin beta chain family.
     
 0.696
itgb8
Integrin beta; Belongs to the integrin beta chain family.
     
 0.691
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.