STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dclre1aDNA cross-link repair 1A (PSO2 homolog, S. cerevisiae). (950 aa)    
Predicted Functional Partners:
cpsf1
Cleavage and polyadenylation specific factor 1.
   
 0.892
sympk
Symplekin.
   
 0.877
ENSELUP00000032389
Uncharacterized protein.
    
 0.869
ints4
Integrator complex subunit 4.
   
 0.858
ENSELUP00000015834
Uncharacterized protein.
   
 0.857
xrcc6
X-ray repair complementing defective repair in Chinese hamster cells 6.
   
 0.854
mus81
MUS81 structure-specific endonuclease subunit.
   
 0.824
fancd2
FA complementation group D2.
   
 0.818
pcf11
PCF11 cleavage and polyadenylation factor subunit.
   
 0.815
fan1
Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.
    
 0.812
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.