node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A0A060VMD1 | A0A060W8Z5 | A0A060VMD1 | A0A060W8Z5 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | CULLIN_2 domain-containing protein; Belongs to the cullin family. | 0.826 |
A0A060VMD1 | A0A060WJP2 | A0A060VMD1 | A0A060WJP2 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | Ubiquitin-like domain-containing protein. | 0.986 |
A0A060VMD1 | A0A060WUL3 | A0A060VMD1 | A0A060WUL3 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | UBX domain-containing protein. | 0.590 |
A0A060VMD1 | A0A060X6K3 | A0A060VMD1 | A0A060X6K3 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | RING-type domain-containing protein. | 0.856 |
A0A060VMD1 | A0A060XJ37 | A0A060VMD1 | A0A060XJ37 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | MPN domain-containing protein. | 0.823 |
A0A060VMD1 | A0A060XTC5 | A0A060VMD1 | A0A060XTC5 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | ULP_PROTEASE domain-containing protein. | 0.871 |
A0A060VMD1 | A0A060Y9G0 | A0A060VMD1 | A0A060Y9G0 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | UBX domain-containing protein. | 0.590 |
A0A060VMD1 | CSN5 | A0A060VMD1 | C1BF76 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | COP9 signalosome complex subunit 5. | 0.823 |
A0A060VMD1 | RBX1 | A0A060VMD1 | C1BEJ3 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | RING-box protein 1. | 0.856 |
A0A060W8Z5 | A0A060VMD1 | A0A060W8Z5 | A0A060VMD1 | CULLIN_2 domain-containing protein; Belongs to the cullin family. | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | 0.826 |
A0A060W8Z5 | A0A060WJP2 | A0A060W8Z5 | A0A060WJP2 | CULLIN_2 domain-containing protein; Belongs to the cullin family. | Ubiquitin-like domain-containing protein. | 0.981 |
A0A060W8Z5 | A0A060WUL3 | A0A060W8Z5 | A0A060WUL3 | CULLIN_2 domain-containing protein; Belongs to the cullin family. | UBX domain-containing protein. | 0.999 |
A0A060W8Z5 | A0A060X1D8 | A0A060W8Z5 | A0A060X1D8 | CULLIN_2 domain-containing protein; Belongs to the cullin family. | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | 0.826 |
A0A060W8Z5 | A0A060X6K3 | A0A060W8Z5 | A0A060X6K3 | CULLIN_2 domain-containing protein; Belongs to the cullin family. | RING-type domain-containing protein. | 0.995 |
A0A060W8Z5 | A0A060XJ37 | A0A060W8Z5 | A0A060XJ37 | CULLIN_2 domain-containing protein; Belongs to the cullin family. | MPN domain-containing protein. | 0.983 |
A0A060W8Z5 | A0A060XTC5 | A0A060W8Z5 | A0A060XTC5 | CULLIN_2 domain-containing protein; Belongs to the cullin family. | ULP_PROTEASE domain-containing protein. | 0.579 |
A0A060W8Z5 | A0A060Y9G0 | A0A060W8Z5 | A0A060Y9G0 | CULLIN_2 domain-containing protein; Belongs to the cullin family. | UBX domain-containing protein. | 0.999 |
A0A060W8Z5 | CSN5 | A0A060W8Z5 | C1BF76 | CULLIN_2 domain-containing protein; Belongs to the cullin family. | COP9 signalosome complex subunit 5. | 0.983 |
A0A060W8Z5 | RBX1 | A0A060W8Z5 | C1BEJ3 | CULLIN_2 domain-containing protein; Belongs to the cullin family. | RING-box protein 1. | 0.995 |
A0A060WJP2 | A0A060VMD1 | A0A060WJP2 | A0A060VMD1 | Ubiquitin-like domain-containing protein. | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | 0.986 |