STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A060WTR3Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (371 aa)    
Predicted Functional Partners:
A0A060X860
Uncharacterized protein.
  
 0.999
A0A060XP10
Uncharacterized protein.
  
 0.999
A0A060ZHR6
Uncharacterized protein; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.997
A0A060W7W3
Histone domain-containing protein; Belongs to the histone H2B family.
   
 0.995
A0A060W843
Histone H2B; Belongs to the histone H2B family.
   
 0.995
A0A060ZUT6
Histone H2A; Belongs to the histone H2A family.
   
0.995
A0A060VYK6
Histone domain-containing protein.
   
 0.969
A0A060W2E3
Histone H3; Belongs to the histone H3 family.
   
 0.969
A0A060WQS0
Histone domain-containing protein.
   
 0.969
A0A060WYH3
Histone domain-containing protein.
   
 0.969
Your Current Organism:
Oncorhynchus mykiss
NCBI taxonomy Id: 8022
Other names: O. mykiss, Oncorhynchus nerka mykiss, Parasalmo mykiss, Salmo mykiss, rainbow trout
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.