STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A060X4V0Perilipin; Belongs to the perilipin family. (442 aa)    
Predicted Functional Partners:
A0A060WI18
AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]
   
  0.842
A0A060WT69
AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]
   
  0.842
A0A060WKL3
Uncharacterized protein.
     
0.834
A0A060WL65
MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.
    
  0.800
A0A060WPF3
MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.
    
  0.800
A0A060WW43
Clat_adaptor_s domain-containing protein.
    
  0.800
A0A060WXF5
MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.
    
  0.800
A0A060WY93
MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.
    
  0.800
A0A060XNF6
V-SNARE coiled-coil homology domain-containing protein.
   
 0.751
A0A060WZJ8
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
  0.736
Your Current Organism:
Oncorhynchus mykiss
NCBI taxonomy Id: 8022
Other names: O. mykiss, Oncorhynchus nerka mykiss, Parasalmo mykiss, Salmo mykiss, rainbow trout
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.