STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A060X4Y9H15 domain-containing protein. (224 aa)    
Predicted Functional Partners:
A0A060ZHR6
Uncharacterized protein; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.980
A0A060WE73
Importin N-terminal domain-containing protein.
    
   0.879
A0A060XF28
Importin N-terminal domain-containing protein.
    
   0.879
A0A060VU69
RPA_C domain-containing protein.
    
 0.852
A0A060WQG6
Uncharacterized protein.
    
 0.852
A0A060WRH2
Uncharacterized protein.
    
 0.852
A0A060XNV6
RPA_C domain-containing protein.
    
 0.852
A0A060XYU5
STN1_2 domain-containing protein.
    
 0.852
A0A060Y1E2
CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.
    
 0.852
A0A060Y5Y0
RPA_C domain-containing protein.
    
 0.852
Your Current Organism:
Oncorhynchus mykiss
NCBI taxonomy Id: 8022
Other names: O. mykiss, Oncorhynchus nerka mykiss, Parasalmo mykiss, Salmo mykiss, rainbow trout
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.