A0A060XF91 protein (Oncorhynchus mykiss) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

A0A060XF91

Uncharacterized protein. (119 aa)

Predicted Functional Partners:

A0A060VTV2

0.837

A0A060Y8V7

0.837

A0A060WA11

0.789

A0A060X419

0.782

A0A060ZBG1

0.683

A0A060YLH9

0.635

A0A060YMC6

0.635

A0A061AC55

0.635

A0A060VTB7

0.519

A0A060WEG6

0.519

Your Current Organism:

Oncorhynchus mykiss

NCBI taxonomy Id: 8022
Other names: O. mykiss, Oncorhynchus nerka mykiss, Parasalmo mykiss, Salmo mykiss, rainbow trout

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A060VTB7	A0A060VTV2	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family.	PKD_channel domain-containing protein.	0.519
A0A060VTB7	A0A060WA11	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family.	PKD_channel domain-containing protein.	0.519
A0A060VTB7	A0A060X419	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family.	PKD_channel domain-containing protein.	0.519
A0A060VTB7	A0A060XF91	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family.	Uncharacterized protein.	0.519
A0A060VTB7	A0A060Y8V7	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family.	PKD_channel domain-containing protein.	0.519
A0A060VTB7	A0A060YLH9	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family.	Uncharacterized protein.	0.747
A0A060VTB7	A0A060YMC6	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family.	Uncharacterized protein.	0.747
A0A060VTB7	A0A060ZBG1	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family.	PKD_channel domain-containing protein.	0.519
A0A060VTB7	A0A061AC55	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family.	LSDAT_euk domain-containing protein.	0.747
A0A060VTV2	A0A060VTB7	PKD_channel domain-containing protein.	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family.	0.519
A0A060VTV2	A0A060WA11	PKD_channel domain-containing protein.	PKD_channel domain-containing protein.	0.792
A0A060VTV2	A0A060WEG6	PKD_channel domain-containing protein.	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family.	0.519
A0A060VTV2	A0A060X419	PKD_channel domain-containing protein.	PKD_channel domain-containing protein.	0.784
A0A060VTV2	A0A060XF91	PKD_channel domain-containing protein.	Uncharacterized protein.	0.837
A0A060VTV2	A0A060YLH9	PKD_channel domain-containing protein.	Uncharacterized protein.	0.635
A0A060VTV2	A0A060YMC6	PKD_channel domain-containing protein.	Uncharacterized protein.	0.635
A0A060VTV2	A0A060ZBG1	PKD_channel domain-containing protein.	PKD_channel domain-containing protein.	0.687
A0A060VTV2	A0A061AC55	PKD_channel domain-containing protein.	LSDAT_euk domain-containing protein.	0.635
A0A060WA11	A0A060VTB7	PKD_channel domain-containing protein.	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family.	0.519
A0A060WA11	A0A060VTV2	PKD_channel domain-containing protein.	PKD_channel domain-containing protein.	0.792

page 1 of 6

Network Stats

number of nodes:

11

number of edges:

41

average node degree:

7.45

avg. local clustering coefficient:

0.853

expected number of edges:

11

PPI enrichment p-value:

3.98e-12

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0034645

Cellular macromolecule biosynthetic process

5 of 239

1.17

0.7

0.0186

GO:0044038

Cell wall macromolecule biosynthetic process

3 of 60

1.55

0.65

0.0498

GO:0009273

Peptidoglycan-based cell wall biogenesis

3 of 61

1.54

0.65

0.0498

GO:1901137

Carbohydrate derivative biosynthetic process

4 of 236

1.08

0.54

0.0498

GO:0016053

Organic acid biosynthetic process

5 of 340

1.01

0.51

0.0498

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016780

Phosphotransferase activity, for other substituted phosphate groups

3 of 20

2.02

1.27

0.0036

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2964

Mixed, incl. CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase , and GtrA-like protein

3 of 6

2.55

2.39

3.49e-05

CL:2923

Mixed, incl. Isoprenoid metabolic process, and Polysaccharide biosynthetic process

8 of 197

1.46

2.21

5.16e-08

CL:2944

Mixed, incl. O-Antigen nucleotide sugar biosynthesis, and Lipopolysaccharide biosynthesis

4 of 35

1.9

2.1

3.49e-05

CL:2937

Mixed, incl. O-Antigen nucleotide sugar biosynthesis, and Polysaccharide biosynthetic process

5 of 66

1.73

2.04

1.97e-05

CL:3193

Mixed, incl. Isoprenoid biosynthetic process, and Encapsulin nanocompartment

3 of 62

1.53

0.99

0.0074

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

kau03060

Protein export

3 of 41

1.71

1.16

0.0040

kau03070

Bacterial secretion system

3 of 49

1.63

1.13

0.0040

kau01053

Biosynthesis of siderophore group nonribosomal peptides

2 of 25

1.75

0.78

0.0308

kau02010

ABC transporters

4 of 357

0.9

0.49

0.0433

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0015629

Actin cytoskeleton

2 of 19

1.87

0.74

0.0389

GOCC:0005886

Plasma membrane

7 of 775

0.8

0.56

0.0085

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00535

Glycosyl transferase family 2

3 of 20

2.02

1.29

0.0033

PF04464

CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase

2 of 2

2.85

1.28

0.0049

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