STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A060XRN6Folate gamma-glutamyl hydrolase. (317 aa)    
Predicted Functional Partners:
A0A060XF08
Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.
     
 0.939
A0A060Z0S2
DHFR domain-containing protein.
     
 0.931
A0A060YKG4
Uncharacterized protein.
     
 0.906
A0A060Z2I3
Uncharacterized protein.
     
 0.906
A0A060X5S1
Thymidylat_synt domain-containing protein.
   
 
 0.902
A0A060WLR2
DHFR domain-containing protein.
     
 0.874
A0A060X2L2
DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.
     
 0.874
A0A060YUW3
Uncharacterized protein.
  
  
 
0.839
A0A060YAY5
zf-C4pol domain-containing protein.
     
 0.837
A0A060VX46
Folate gamma-glutamyl hydrolase.
  
  
 
0.836
Your Current Organism:
Oncorhynchus mykiss
NCBI taxonomy Id: 8022
Other names: O. mykiss, Oncorhynchus nerka mykiss, Parasalmo mykiss, Salmo mykiss, rainbow trout
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.