A0A060XVQ0 protein (Oncorhynchus mykiss) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

A0A060XVQ0

Uncharacterized protein; Belongs to the beta/gamma-crystallin family. (193 aa)

Predicted Functional Partners:

A0A060WHE9

0.793

A0A060XVQ8

0.791

A0A060YX29

0.791

A0A060XW11

0.409

A0A060WQY9

0.403

A0A060ZHA2

0.403

A0A060YPH0

0.401

Your Current Organism:

Oncorhynchus mykiss

NCBI taxonomy Id: 8022
Other names: O. mykiss, Oncorhynchus nerka mykiss, Parasalmo mykiss, Salmo mykiss, rainbow trout

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A060WHE9	A0A060XVQ0	Uncharacterized protein; Belongs to the beta/gamma-crystallin family.	Uncharacterized protein; Belongs to the beta/gamma-crystallin family.	0.793
A0A060WQY9	A0A060XVQ0	B30.2/SPRY domain-containing protein.	Uncharacterized protein; Belongs to the beta/gamma-crystallin family.	0.403
A0A060XVQ0	A0A060WHE9	Uncharacterized protein; Belongs to the beta/gamma-crystallin family.	Uncharacterized protein; Belongs to the beta/gamma-crystallin family.	0.793
A0A060XVQ0	A0A060WQY9	Uncharacterized protein; Belongs to the beta/gamma-crystallin family.	B30.2/SPRY domain-containing protein.	0.403
A0A060XVQ0	A0A060XVQ8	Uncharacterized protein; Belongs to the beta/gamma-crystallin family.	Uncharacterized protein; Belongs to the beta/gamma-crystallin family.	0.791
A0A060XVQ0	A0A060XW11	Uncharacterized protein; Belongs to the beta/gamma-crystallin family.	B30.2/SPRY domain-containing protein.	0.409
A0A060XVQ0	A0A060YPH0	Uncharacterized protein; Belongs to the beta/gamma-crystallin family.	Uncharacterized protein; Belongs to the beta/gamma-crystallin family.	0.401
A0A060XVQ0	A0A060YX29	Uncharacterized protein; Belongs to the beta/gamma-crystallin family.	Uncharacterized protein; Belongs to the beta/gamma-crystallin family.	0.791
A0A060XVQ0	A0A060ZHA2	Uncharacterized protein; Belongs to the beta/gamma-crystallin family.	PSI domain-containing protein.	0.403
A0A060XVQ8	A0A060XVQ0	Uncharacterized protein; Belongs to the beta/gamma-crystallin family.	Uncharacterized protein; Belongs to the beta/gamma-crystallin family.	0.791
A0A060XW11	A0A060XVQ0	B30.2/SPRY domain-containing protein.	Uncharacterized protein; Belongs to the beta/gamma-crystallin family.	0.409
A0A060YPH0	A0A060XVQ0	Uncharacterized protein; Belongs to the beta/gamma-crystallin family.	Uncharacterized protein; Belongs to the beta/gamma-crystallin family.	0.401
A0A060YX29	A0A060XVQ0	Uncharacterized protein; Belongs to the beta/gamma-crystallin family.	Uncharacterized protein; Belongs to the beta/gamma-crystallin family.	0.791
A0A060ZHA2	A0A060XVQ0	PSI domain-containing protein.	Uncharacterized protein; Belongs to the beta/gamma-crystallin family.	0.403

Network Stats

number of nodes:

11

number of edges:

31

average node degree:

5.64

avg. local clustering coefficient:

0.429

expected number of edges:

16

PPI enrichment p-value:

0.000631

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0044205

De novo UMP biosynthetic process

5 of 8

2.3

3.42

1.53e-07

GO:0009112

Nucleobase metabolic process

5 of 19

1.93

2.88

3.56e-07

GO:0046112

Nucleobase biosynthetic process

4 of 9

2.16

2.81

2.05e-06

GO:0009156

Ribonucleoside monophosphate biosynthetic process

6 of 33

1.77

2.75

1.53e-07

GO:0009084

Glutamine family amino acid biosynthetic process

5 of 23

1.85

2.68

6.36e-07

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004088

Carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity

2 of 2

2.51

0.8

0.0355

GO:0016743

Carboxyl- or carbamoyltransferase activity

2 of 4

2.21

0.79

0.0355

GO:0016597

Amino acid binding

2 of 3

2.33

0.79

0.0355

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

10 of 1079

0.48

0.36

0.0075

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:768

De novo UMP biosynthetic process

5 of 8

2.3

3.72

3.27e-08

CL:715

Ribonucleoside monophosphate metabolic process, and IMP dehydrogenase activity

7 of 37

1.79

3.17

6.78e-09

CL:1254

Glutamine family amino acid biosynthetic process, and Glycine catabolic process

3 of 36

1.43

0.75

0.0249

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

tbi00250

Alanine, aspartate and glutamate metabolism

6 of 27

1.86

3.19

1.86e-08

tbi00240

Pyrimidine metabolism

6 of 27

1.86

3.19

1.86e-08

tbi01100

Metabolic pathways

11 of 670

0.72

4.15e-07

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0665

Pyrimidine biosynthesis

5 of 10

2.21

3.52

5.72e-08

KW-0055

Arginine biosynthesis

3 of 9

2.03

1.69

0.00047

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF02729

Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain

2 of 2

2.51

0.85

0.0284

PF00185

Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain

2 of 2

2.51

0.85

0.0284

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (28%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2024

Credits

Access

Info

About