A0A060YH71 protein (Oncorhynchus mykiss) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

A0A060YH71

Uncharacterized protein. (788 aa)

Predicted Functional Partners:

A0A060WQP5

0.676

A0A060XTA5

0.676

A0A060XTW9

0.676

A0A060Y422

0.676

A0A060YGE0

0.676

A0A060YP29

0.676

A0A060ZB44

0.676

A0A060ZX64

0.676

A0A060WVP1

0.634

A0A060XDD3

0.634

Your Current Organism:

Oncorhynchus mykiss

NCBI taxonomy Id: 8022
Other names: O. mykiss, Oncorhynchus nerka mykiss, Parasalmo mykiss, Salmo mykiss, rainbow trout

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A060WQP5	A0A060WVP1	Uncharacterized protein.	Uncharacterized protein.	0.829
A0A060WQP5	A0A060XDD3	Uncharacterized protein.	Uncharacterized protein.	0.825
A0A060WQP5	A0A060XTW9	Uncharacterized protein.	Uncharacterized protein.	0.783
A0A060WQP5	A0A060YH71	Uncharacterized protein.	Uncharacterized protein.	0.676
A0A060WQP5	A0A060YP29	Uncharacterized protein.	Uncharacterized protein.	0.781
A0A060WQP5	A0A060ZX64	Uncharacterized protein.	Myotubularin phosphatase domain-containing protein.	0.784
A0A060WVP1	A0A060WQP5	Uncharacterized protein.	Uncharacterized protein.	0.829
A0A060WVP1	A0A060XDD3	Uncharacterized protein.	Uncharacterized protein.	0.834
A0A060WVP1	A0A060XTA5	Uncharacterized protein.	Uncharacterized protein.	0.597
A0A060WVP1	A0A060XTW9	Uncharacterized protein.	Uncharacterized protein.	0.717
A0A060WVP1	A0A060Y422	Uncharacterized protein.	Myotubularin phosphatase domain-containing protein.	0.597
A0A060WVP1	A0A060YGE0	Uncharacterized protein.	Uncharacterized protein.	0.829
A0A060WVP1	A0A060YH71	Uncharacterized protein.	Uncharacterized protein.	0.634
A0A060WVP1	A0A060YP29	Uncharacterized protein.	Uncharacterized protein.	0.717
A0A060WVP1	A0A060ZB44	Uncharacterized protein.	Uncharacterized protein.	0.609
A0A060WVP1	A0A060ZX64	Uncharacterized protein.	Myotubularin phosphatase domain-containing protein.	0.717
A0A060XDD3	A0A060WQP5	Uncharacterized protein.	Uncharacterized protein.	0.825
A0A060XDD3	A0A060WVP1	Uncharacterized protein.	Uncharacterized protein.	0.834
A0A060XDD3	A0A060XTA5	Uncharacterized protein.	Uncharacterized protein.	0.597
A0A060XDD3	A0A060XTW9	Uncharacterized protein.	Uncharacterized protein.	0.597

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

54

average node degree:

9.82

avg. local clustering coefficient:

0.982

expected number of edges:

92

PPI enrichment p-value:

0.665

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016989

Sigma factor antagonist activity

3 of 5

2.41

1.96

0.00021

GO:0015343

Siderophore transmembrane transporter activity

3 of 13

2.0

1.56

0.00085

GO:0060089

Molecular transducer activity

5 of 63

1.53

0.00019

GO:0031992

Energy transducer activity

2 of 2

2.63

1.31

0.0040

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0031224

Intrinsic component of membrane

10 of 1169

0.56

0.45

0.0012

GO:0016021

Integral component of membrane

9 of 1162

0.52

0.39

0.0059

GO:0016020

Membrane

11 of 1689

0.45

0.37

0.0012

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:36618666

(2022) Responses of the bacterial community of tobacco phyllosphere to summer climate and wildfire disease.

2 of 2

2.63

1.3

0.0042

PMID:36677491

(2023) Sphingomonas sediminicola Is an Endosymbiotic Bacterium Able to Induce the Formation of Root Nodules in Pea (Pisum sativum L.) and to Enhance Plant Biomass Production.

3 of 17

1.88

1.27

0.0030

PMID:24319357

(2013) Engineering rhizobial bioinoculants: a strategy to improve iron nutrition.

2 of 12

1.85

0.72

0.0421

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:979

Mixed, incl. Protein insertion into membrane, and Energy transducer activity

6 of 20

2.11

3.76

7.50e-09

CL:981

Mixed, incl. Energy transducer activity, and Biopolymer transport protein ExbD/TolR

5 of 12

2.25

3.51

7.98e-08

CL:995

Mixed, incl. Energy transducer activity, and Biopolymer transport protein ExbD/TolR

4 of 5

2.54

3.3

5.52e-07

CL:5671

FecR protein, and TonB-dependent siderophore receptor

4 of 10

2.23

2.76

3.49e-06

CL:5675

FecR protein, and Secretin/TonB, short N-terminal domain

3 of 5

2.41

2.2

7.24e-05

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005887

Integral component of plasma membrane

4 of 87

1.29

0.81

0.0125

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF16220

Domain of unknown function (DUF4880)

3 of 3

2.63

2.12

0.00012

PF04773

FecR protein

3 of 3

2.63

2.12

0.00012

PF03544

Gram-negative bacterial TonB protein C-terminal

2 of 3

2.46

1.08

0.0107

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR032623

FecR, N-terminal

3 of 3

2.63

1.9

0.00032

IPR012373

Fe(2+)-dicitrate sensor, transmembrane component

3 of 3

2.63

1.9

0.00032

IPR006860

FecR protein

3 of 3

2.63

1.9

0.00032

IPR006260

TonB/TolA, C-terminal

2 of 3

2.46

0.92

0.0213

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (26%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2024

Credits

Access

Info

About