STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
exd2Exonuclease 3'-5' domain-containing protein 2. (421 aa)    
Predicted Functional Partners:
exo1
Exonuclease 1.
   
 0.866
DNA2
DNA replication ATP-dependent helicase/nuclease DNA2.
   
 
 0.830
rpa3
Replication protein A3.
    
 0.830
LOC106570310
Replication protein A 14 kDa subunit-like.
    
 0.830
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.830
ENSSSAP00000025751
annotation not available
    
 0.825
rad52
DNA repair protein RAD52 homolog.
    
 0.822
xrcc3
DNA repair protein XRCC3.
    
 0.800
ENSSSAP00000064605
annotation not available
    
 0.740
LOC106582297
BRCA1-associated RING domain protein 1-like isoform X1.
    
 0.740
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.