STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC106602320Probable E3 ubiquitin-protein ligase HERC6. (725 aa)    
Predicted Functional Partners:
ube2l3
Ubiquitin-conjugating enzyme E2 L3-like; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.710
LOC106612584
E3 ubiquitin-protein ligase TRIP12-like isoform X1.
   
 
0.688
LOC106580884
E3 ubiquitin-protein ligase TRIP12 isoform X1.
   
 
0.688
rig-I
Retinoic acid-inducible gene-I.
   
 
 0.568
ENSSSAP00000097191
annotation not available
    
 0.566
ub2l3
Salmo salar Ubiquitin-conjugating enzyme E2 L3 (ub2l3), mRNA.
    
 0.566
ifih1
Interferon-induced helicase C domain-containing protein 1 isoform X1.
   
 
 0.558
irf-3
Interferon regulatory factor 3 isoform X1.
   
 0.542
mx2
Myxovirus resistance 2 isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
   
 
 0.517
ATG7
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]
   
 0.512
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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