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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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filled nodes:
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LOC106591641Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (359 aa)    
Predicted Functional Partners:
LOC106576591
DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
  
 0.966
LOC106576591-2
DNA-(apurinic or apyrimidinic site) lyase-like.
  
 0.966
apex1
Salmo salar APEX nuclease (multifunctional DNA repair enzyme) 1 (apex1), mRNA.
  
 0.966
apex2
DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
  
 0.946
LOC106567314
DNA-(Apurinic or apyrimidinic site) lyase 2-like.
  
 0.946
ercc4
DNA repair endonuclease XPF.
    
 
 0.935
mlh1
DNA mismatch repair protein Mlh1.
  
 
 0.927
ogg1
N-glycosylase/DNA lyase isoform X1.
   
 
 0.896
ung
Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
   
 0.894
mutyh
Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.
    
 0.893
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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