STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
srebf2Sterol regulatory element-binding protein 2 isoform X1. (1160 aa)    
Predicted Functional Partners:
LOC106605338
Sterol regulatory element-binding protein cleavage-activating protein-like isoform X1.
    
 0.927
SCAP
Sterol regulatory element-binding protein cleavage-activating protein-like isoform X4.
    
 0.927
ENSSSAP00000080471
annotation not available
    
 0.913
LOC106600802
Importin subunit beta-1-like isoform X2.
    
 0.877
LOC106607509
Importin subunit beta-1 isoform X2.
    
 0.877
hmgcr
3-hydroxy-3-methylglutaryl coenzyme A reductase.
   
 0.863
LOC106611923
Peroxisome proliferator-activated receptor gamma coactivator 1-beta-like.
    
 0.845
LOC100136477
Peroxisome proliferator-activated receptor gamma coactivator 1-beta isoform X1.
    
 0.845
NPC1L1
Niemann-Pick C1-like protein 1.
    
 0.834
LOC100195848
Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 
 0.826
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
Server load: low (34%) [HD]