LOC106590064 protein (Salmo salar) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

LOC106590064

Kelch-like ECH-associated protein 1. (630 aa)

Predicted Functional Partners:

LOC106575067

0.956

LOC106586247

0.956

nf2l2

0.956

LOC106612448

0.894

LOC106600593

0.894

LOC106580681

0.894

CUL3

0.890

LOC100194694

0.881

sqstm

0.881

rbx1

0.877

Your Current Organism:

Salmo salar

NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUL3	LOC100194694	ENSSSAP00000077305	ENSSSAP00000097368	Cullin-3-like; Belongs to the cullin family.	Uncharacterized protein LOC100194694.	0.926
CUL3	LOC106575067	ENSSSAP00000077305	ENSSSAP00000014859	Cullin-3-like; Belongs to the cullin family.	Nuclear factor erythroid 2-related factor 2-like isoform X1.	0.910
CUL3	LOC106586247	ENSSSAP00000077305	ENSSSAP00000074090	Cullin-3-like; Belongs to the cullin family.	Nuclear factor erythroid 2-related factor 2-like.	0.910
CUL3	LOC106590064	ENSSSAP00000077305	ENSSSAP00000001398	Cullin-3-like; Belongs to the cullin family.	Kelch-like ECH-associated protein 1.	0.890
CUL3	nf2l2	ENSSSAP00000077305	ENSSSAP00000095802	Cullin-3-like; Belongs to the cullin family.	Nuclear factor erythroid 2-related factor 2.	0.910
CUL3	rbx1	ENSSSAP00000077305	ENSSSAP00000005050	Cullin-3-like; Belongs to the cullin family.	RING-box protein 1; E3 ubiquitin ligase component of multiple cullin-RING-based E3 ubiquitin-protein ligase (CRLs) complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins, including proteins involved in cell cycle progression, signal transduction, transcription and transcription-coupled nucleotide excision repair. CRLs complexes and arih1 collaborate in tandem to mediate ubiquitination of target proteins, arih1 mediating addition of the first ubiquitin on CRLs targets. The functional specificity of the E3 ubiquitin-protein ligase complexes d [...]	0.968
CUL3	sqstm	ENSSSAP00000077305	ENSSSAP00000104849	Cullin-3-like; Belongs to the cullin family.	Sequestosome-1.	0.926
LOC100194694	CUL3	ENSSSAP00000097368	ENSSSAP00000077305	Uncharacterized protein LOC100194694.	Cullin-3-like; Belongs to the cullin family.	0.926
LOC100194694	LOC106575067	ENSSSAP00000097368	ENSSSAP00000014859	Uncharacterized protein LOC100194694.	Nuclear factor erythroid 2-related factor 2-like isoform X1.	0.876
LOC100194694	LOC106580681	ENSSSAP00000097368	ENSSSAP00000106226	Uncharacterized protein LOC100194694.	Cullin-3; Belongs to the cullin family.	0.926
LOC100194694	LOC106586247	ENSSSAP00000097368	ENSSSAP00000074090	Uncharacterized protein LOC100194694.	Nuclear factor erythroid 2-related factor 2-like.	0.876
LOC100194694	LOC106590064	ENSSSAP00000097368	ENSSSAP00000001398	Uncharacterized protein LOC100194694.	Kelch-like ECH-associated protein 1.	0.881
LOC100194694	LOC106600593	ENSSSAP00000097368	ENSSSAP00000077209	Uncharacterized protein LOC100194694.	Cullin-3-like; Belongs to the cullin family.	0.926
LOC100194694	LOC106612448	ENSSSAP00000097368	ENSSSAP00000047131	Uncharacterized protein LOC100194694.	Cullin-3-like.	0.926
LOC100194694	nf2l2	ENSSSAP00000097368	ENSSSAP00000095802	Uncharacterized protein LOC100194694.	Nuclear factor erythroid 2-related factor 2.	0.876
LOC100194694	rbx1	ENSSSAP00000097368	ENSSSAP00000005050	Uncharacterized protein LOC100194694.	RING-box protein 1; E3 ubiquitin ligase component of multiple cullin-RING-based E3 ubiquitin-protein ligase (CRLs) complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins, including proteins involved in cell cycle progression, signal transduction, transcription and transcription-coupled nucleotide excision repair. CRLs complexes and arih1 collaborate in tandem to mediate ubiquitination of target proteins, arih1 mediating addition of the first ubiquitin on CRLs targets. The functional specificity of the E3 ubiquitin-protein ligase complexes d [...]	0.713
LOC106575067	CUL3	ENSSSAP00000014859	ENSSSAP00000077305	Nuclear factor erythroid 2-related factor 2-like isoform X1.	Cullin-3-like; Belongs to the cullin family.	0.910
LOC106575067	LOC100194694	ENSSSAP00000014859	ENSSSAP00000097368	Nuclear factor erythroid 2-related factor 2-like isoform X1.	Uncharacterized protein LOC100194694.	0.876
LOC106575067	LOC106580681	ENSSSAP00000014859	ENSSSAP00000106226	Nuclear factor erythroid 2-related factor 2-like isoform X1.	Cullin-3; Belongs to the cullin family.	0.910
LOC106575067	LOC106590064	ENSSSAP00000014859	ENSSSAP00000001398	Nuclear factor erythroid 2-related factor 2-like isoform X1.	Kelch-like ECH-associated protein 1.	0.956