STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
smg1Serine/threonine-protein kinase SMG1; Belongs to the PI3/PI4-kinase family. (3214 aa)    
Predicted Functional Partners:
smg9
Protein SMG9; Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with smg1 and smg8 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required for the efficient association between smg1 and smg8 (By similarity); Belongs to the SMG9 family.
    
 0.985
ENSSSAP00000023187
annotation not available
    
 0.985
LOC106603437
Protein SMG8-like.
   
 0.984
LOC106567695
Protein SMG8-like.
   
 0.984
mapkap1
Stress-activated map kinase-interacting protein 1.
    
 0.984
rraga
Ras-related GTP-binding protein A isoform X1.
    
 0.983
ncbp2
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]
    
 
 0.983
LOC106569064
Protein SMG7-like isoform X2.
   
 0.981
smg7
Protein SMG7 isoform X1.
   
 0.981
LOC106588110
Regulatory-associated protein of mTOR isoform X2.
   
 0.969
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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