Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC106601398Sphingosine kinase 1-like isoform X2. (546 aa)    
Predicted Functional Partners:
asah2
Neutral ceramidase.
    
 0.923
ENSSSAP00000108065
Alkaline ceramidase 3.
     
 0.912
LOC106608622
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
     
 0.909
sgpp1
Sphingosine-1-phosphate phosphatase 1.
   
 0.901
LOC106571508
Sphingosine-1-phosphate phosphatase 1-like isoform X1.
   
 0.901
LOC106604578
Sphingosine-1-phosphate lyase 1-like isoform X1.
  
 0.896
LOC106576820
Sphingosine-1-phosphate lyase 1-like.
  
 0.896
gba2
Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.
     
 0.896
degs2
Sphingolipid delta(4)-desaturase/C4-hydroxylase DES2.
    
 0.887
LOC106609942
Acid ceramidase-like; Belongs to the acid ceramidase family.
     
 0.875
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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