DLL4 protein (Salmo salar) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

DLL4

Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (703 aa)

Predicted Functional Partners:

LOC106579992

0.929

NOTCH1

0.929

LOC106584380

0.856

LOC106613830

0.856

LOC106560538

0.807

ENSSSAP00000028146

0.650

LOC106571366

0.558

rbpj

0.543

ENSSSAP00000008726

0.543

ENSSSAP00000028387

0.543

Your Current Organism:

Salmo salar

NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DLL4	ENSSSAP00000008726	ENSSSAP00000002793	ENSSSAP00000008726	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	annotation not available	0.543
DLL4	ENSSSAP00000028146	ENSSSAP00000002793	ENSSSAP00000028146	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Neurogenic locus notch homolog protein 1-like.	0.650
DLL4	ENSSSAP00000028387	ENSSSAP00000002793	ENSSSAP00000028387	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Recombining binding protein suppressor of hairless-like.	0.543
DLL4	LOC106560538	ENSSSAP00000002793	ENSSSAP00000024188	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Neurogenic locus notch homolog protein 1-like isoform X1.	0.807
DLL4	LOC106571366	ENSSSAP00000002793	ENSSSAP00000117952	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Hairy/enhancer-of-split related with YRPW motif protein 2.	0.558
DLL4	LOC106579992	ENSSSAP00000002793	ENSSSAP00000016443	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Neurogenic locus notch homolog protein 1-like isoform X1.	0.929
DLL4	LOC106584380	ENSSSAP00000002793	ENSSSAP00000088750	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Neurogenic locus notch homolog protein 2-like isoform X1.	0.856
DLL4	LOC106613830	ENSSSAP00000002793	ENSSSAP00000091348	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 2-like.	0.856
DLL4	NOTCH1	ENSSSAP00000002793	ENSSSAP00000073878	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Neurogenic locus notch homolog protein 1-like isoform X1.	0.929
DLL4	rbpj	ENSSSAP00000002793	ENSSSAP00000007655	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Recombining binding protein suppressor of hairless.	0.543
ENSSSAP00000008726	DLL4	ENSSSAP00000008726	ENSSSAP00000002793	annotation not available	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.543
ENSSSAP00000008726	LOC106560538	ENSSSAP00000008726	ENSSSAP00000024188	annotation not available	Neurogenic locus notch homolog protein 1-like isoform X1.	0.947
ENSSSAP00000008726	LOC106571366	ENSSSAP00000008726	ENSSSAP00000117952	annotation not available	Hairy/enhancer-of-split related with YRPW motif protein 2.	0.411
ENSSSAP00000008726	LOC106579992	ENSSSAP00000008726	ENSSSAP00000016443	annotation not available	Neurogenic locus notch homolog protein 1-like isoform X1.	0.947
ENSSSAP00000008726	LOC106584380	ENSSSAP00000008726	ENSSSAP00000088750	annotation not available	Neurogenic locus notch homolog protein 2-like isoform X1.	0.837
ENSSSAP00000008726	LOC106613830	ENSSSAP00000008726	ENSSSAP00000091348	annotation not available	LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 2-like.	0.837
ENSSSAP00000008726	NOTCH1	ENSSSAP00000008726	ENSSSAP00000073878	annotation not available	Neurogenic locus notch homolog protein 1-like isoform X1.	0.947
ENSSSAP00000028146	DLL4	ENSSSAP00000028146	ENSSSAP00000002793	Neurogenic locus notch homolog protein 1-like.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.650
ENSSSAP00000028146	ENSSSAP00000028387	ENSSSAP00000028146	ENSSSAP00000028387	Neurogenic locus notch homolog protein 1-like.	Recombining binding protein suppressor of hairless-like.	0.740
ENSSSAP00000028146	rbpj	ENSSSAP00000028146	ENSSSAP00000007655	Neurogenic locus notch homolog protein 1-like.	Recombining binding protein suppressor of hairless.	0.740