STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ku70ATP-dependent DNA helicase 2 subunit 1 isoform X1. (619 aa)    
Predicted Functional Partners:
wrn
Werner syndrome ATP-dependent helicase isoform X2.
   
 
 0.999
prkdc
DNA-dependent protein kinase catalytic subunit; Belongs to the PI3/PI4-kinase family.
   
 0.994
lig4
DNA ligase.
   
 0.990
rad52
DNA repair protein RAD52 homolog.
   
 
 0.987
ENSSSAP00000030774
annotation not available
   
 0.986
MRE11
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
   
 0.986
Mre11
MRE11 homolog, double strand break repair nuclease.
   
 0.986
rad50
DNA repair protein RAD50.
   
 0.986
LOC106585761
DNA repair protein XRCC4-like isoform X1.
    
 0.973
aplf
Aprataxin and PNK-like factor isoform X1.
    
 
 0.972
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.