STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC106599723NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (304 aa)    
Predicted Functional Partners:
nadsyn1
Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.
    
 0.945
nnmt
Nicotinamide N-methyltransferase.
     
 0.906
nudt12
Peroxisomal NADH pyrophosphatase NUDT12.
    
  0.904
wrn
Werner syndrome ATP-dependent helicase isoform X2.
  
 
 0.824
LOC106612810
Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family.
    
 0.814
SIRT2
NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.
  
 
0.774
nmnat3
Nicotinamide-nucleotide adenylyltransferase.
   
 0.759
LOC106569066
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2.
   
 0.759
nmnat2
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2.
   
 0.759
nmnat1
Nicotinamide-nucleotide adenylyltransferase.
   
 0.759
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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