STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC106604789F-box/WD repeat-containing protein 11-like isoform X1. (700 aa)    
Predicted Functional Partners:
ctnnb1
Catenin beta-1.
    
 0.997
SKP1-2
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 0.997
LOC106599302
Cullin-1; Belongs to the cullin family.
   
 0.995
LOC106569218
Cullin-1-like; Belongs to the cullin family.
   
 0.995
CUL1
Cullin-1-like; Belongs to the cullin family.
   
 0.995
rbx1
RING-box protein 1; E3 ubiquitin ligase component of multiple cullin-RING-based E3 ubiquitin-protein ligase (CRLs) complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins, including proteins involved in cell cycle progression, signal transduction, transcription and transcription-coupled nucleotide excision repair. CRLs complexes and arih1 collaborate in tandem to mediate ubiquitination of target proteins, arih1 mediating addition of the first ubiquitin on CRLs targets. The functional specificity of the E3 ubiquitin-protein ligase complexes d [...]
    
 0.982
SKP1
S-phase kinase associated protein 1.
    
 0.978
SKP2
S-phase kinase-associated protein 2-like isoform X1.
    
 0.943
LOC106563829
S-phase kinase-associated protein 2-like isoform X1.
    
 0.943
LOC106610174
F-box/WD repeat-containing protein 7-like isoform X2.
  
0.926
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.