STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC106606559TOM1-like protein 2. (323 aa)    
Predicted Functional Partners:
LOC106565756
Macrophage-stimulating protein receptor-like.
    
  0.648
LOC106573120
Hepatocyte growth factor receptor-like.
    
  0.648
ENSSSAP00000046816
Hepatocyte growth factor receptor-like.
    
  0.648
LOC106582756
Macrophage-stimulating protein receptor-like.
    
  0.648
LOC106561553
Hepatocyte growth factor receptor-like.
    
  0.648
LOC106582868
Macrophage-stimulating protein receptor-like.
    
  0.648
LOC100169858
Toll-interacting protein-like.
    
 
 0.633
LOC106587464
Toll-interacting protein; Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (By similarity).
    
 
 0.633
LOC106567664
Rab5 GDP/GTP exchange factor-like.
     
 0.605
rabgef1
Rab5 GDP/GTP exchange factor isoform X2.
     
 0.605
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.