STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100846972Estrogen receptor beta 2 isoform X1. (606 aa)    
Predicted Functional Partners:
LOC100846969
Nuclear Progesterone receptor.
   
0.913
sp1
Transcription factor Sp1 isoform X2.
    
 0.881
med1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 0.869
LOC106603552
Nuclear receptor-interacting protein 1-like.
    
 0.821
LOC106567930
Nuclear receptor-interacting protein 1-like.
    
 0.821
brca1
Breast cancer type 1 susceptibility protein isoform X2.
    
 
 0.812
LOC106608924
Histone acetyltransferase p300-like isoform X2.
    
 0.810
xpp3
Histone acetyltransferase p300-like isoform X8.
    
 0.810
LOC106589530
CREB-binding protein-like isoform X4.
    
 0.810
LOC106607167
Histone acetyltransferase p300-like isoform X9.
    
 0.810
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.