STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSSSAP00000005266Thrombomodulin. (345 aa)    
Predicted Functional Partners:
LOC106587117
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
    
 0.964
LOC106561958
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
    
 0.964
proc
Vitamin K-dependent protein C.
    
 0.809
GAB1
GRB2-associated-binding protein 1 isoform X3.
    
 0.752
LOC106574243
Mitogen-activated protein kinase kinase kinase 2-like.
    
 0.701
SERPINE1
Plasminogen activator inhibitor 1-like; Belongs to the serpin family.
    
 0.699
LOC106608947
Plasminogen activator inhibitor 1-like; Belongs to the serpin family.
    
 0.699
ptpn13
Tyrosine-protein phosphatase non-receptor type 13 isoform X2.
    
 0.636
ENSSSAP00000063903
Caspase 2, apoptosis-related cysteine peptidase.
    
 0.631
pdcd4
Salmo salar Programmed cell death protein 4 (pdcd4), mRNA.
     
 0.609
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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