STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC106610674Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (828 aa)    
Predicted Functional Partners:
rcor1
REST corepressor 1 isoform X2.
   
 0.983
LOC106585063
REST corepressor 3-like isoform X1.
   
 0.979
rcor2
REST corepressor 2.
   
 0.979
LOC106564802
REST corepressor 3-like isoform X2.
   
 0.979
LOC106613768
annotation not available
   
 0.974
HMG20B
annotation not available
   
 0.974
hmg20a
High mobility group protein 20A isoform X1.
   
 0.939
LOC106606187
Putative oxidoreductase GLYR1.
    
 
 0.927
GLYR1
Putative oxidoreductase GLYR1.
    
 
 0.927
LOC106587113
PHD finger protein 21A-like isoform X4.
    
 0.926
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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