STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIO2Iodothyronine deiodinase 2. (268 aa)    
Predicted Functional Partners:
dio1
Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine).
     
0.879
thrb
Thyroid hormone receptor beta isoform X2.
      
 0.830
LOC106588669
Thyroid hormone receptor beta isoform X2.
      
 0.800
LOC106567505
Gamma-aminobutyric acid receptor subunit alpha-1-like isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
      
 0.751
LOC100380670
Gamma-aminobutyric acid receptor subunit alpha-1 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
      
 0.751
tr-alpha
Thyroid hormone receptor alpha.
      
 0.729
ttr
Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
      
 0.727
LOC106589304
Thyroid hormone receptor alpha-like isoform X2.
      
 0.699
LOC106570447
Gamma-aminobutyric acid type B receptor subunit 2-like isoform X1.
      
 0.650
LOC106588960
Gamma-aminobutyric acid type B receptor subunit 2-like.
      
 0.650
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.