STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDGFRBPlatelet-derived growth factor receptor beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1109 aa)    
Predicted Functional Partners:
grb2
Growth factor receptor-bound protein 2 isoform X1.
   
 0.977
LOC106564671
Growth factor receptor-bound protein 2-like.
   
 0.977
LOC106591430
Ell-associated factor Eaf-like; Belongs to the PDGF/VEGF growth factor family.
   
 0.966
ENSSSAP00000065329
Platelet-derived growth factor subunit B.
   
 0.966
plcg2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
    
 0.947
plcg1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
    
 0.947
LOC106560399
Phosphoinositide phospholipase C.
    
 0.947
LOC106606462
Platelet-derived growth factor subunit A-like isoform X1; Belongs to the PDGF/VEGF growth factor family.
    
 0.937
LOC106610161
Vascular endothelial growth factor C-like isoform X1; Belongs to the PDGF/VEGF growth factor family.
    
 0.935
vegfc
Vascular endothelial growth factor C precursor; Belongs to the PDGF/VEGF growth factor family.
    
 0.934
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.