STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC106606819Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. (362 aa)    
Predicted Functional Partners:
trrap
Transformation/transcription domain-associated protein isoform X8; Belongs to the PI3/PI4-kinase family.
    
 0.964
supt3h
Transcription initiation protein SPT3 homolog.
    
 0.957
supt20h
Transcription factor SPT20 homolog.
    
 0.923
LOC106583669
Transcription factor SPT20 homolog isoform X3.
    
 0.923
LOC106579013
Ubiquitin carboxyl-terminal hydrolase.
    
 0.916
LOC106589337
Ubiquitin carboxyl-terminal hydrolase.
    
 0.916
LOC106604983
Transcription initiation factor TFIID subunit 12-like.
    
 0.906
taf12
Transcription initiation factor TFIID subunit 12 isoform X1.
    
 0.906
taf6l
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L.
    
 0.906
LOC106605055
Transcription and mRNA export factor ENY2-2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 comple [...]
    
 0.899
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.