STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC106608413E3 ubiquitin-protein ligase Topors-like. (915 aa)    
Predicted Functional Partners:
LOC106607450
SUMO-conjugating enzyme UBC9-like; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.721
LOC106600883
SUMO-conjugating enzyme UBC9-like.
    
 0.721
ube2i-2
SUMO-conjugating enzyme UBC9 isoform X1; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.721
SUMO1
Small Ubiquitin-related modifier 1.
    
 0.695
LOC106574244
Small ubiquitin-related modifier.
    
 0.695
LOC106582552
Small ubiquitin-related modifier.
    
 0.695
LOC106579288
BTB/POZ domain-containing protein KCTD5-like.
    
 0.682
LOC106589267
BTB/POZ domain-containing protein KCTD5-like.
    
 0.682
LOC106608673
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 
 0.670
tp53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 
 0.670
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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