HTR4 protein (Salmo salar) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

HTR4

5-hydroxytryptamine receptor 4-like isoform X1; Belongs to the G-protein coupled receptor 1 family. (431 aa)

Predicted Functional Partners:

LOC106566693

0.855

LOC106590334

0.855

GNAL

0.855

LOC106596458

0.791

trpa1

0.655

slc27a4

0.641

ENSSSAP00000023970

0.633

LOC106567725

0.633

GNB4

0.622

LOC106567879

0.622

Your Current Organism:

Salmo salar

NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSSAP00000023970	HTR4	ENSSSAP00000023970	ENSSSAP00000009273	5-hydroxytryptamine (serotonin) receptor 3A.	5-hydroxytryptamine receptor 4-like isoform X1; Belongs to the G-protein coupled receptor 1 family.	0.633
ENSSSAP00000023970	slc27a4	ENSSSAP00000023970	ENSSSAP00000020958	5-hydroxytryptamine (serotonin) receptor 3A.	Long-chain fatty acid transport protein 4.	0.622
ENSSSAP00000023970	trpa1	ENSSSAP00000023970	ENSSSAP00000038592	5-hydroxytryptamine (serotonin) receptor 3A.	Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family.	0.620
GNAL	GNB4	ENSSSAP00000111640	ENSSSAP00000005848	Guanine nucleotide-binding protein G(olf) subunit alpha-like.	Guanine nucleotide-binding protein subunit beta-4.	0.763
GNAL	HTR4	ENSSSAP00000111640	ENSSSAP00000009273	Guanine nucleotide-binding protein G(olf) subunit alpha-like.	5-hydroxytryptamine receptor 4-like isoform X1; Belongs to the G-protein coupled receptor 1 family.	0.855
GNAL	LOC106567879	ENSSSAP00000111640	ENSSSAP00000034767	Guanine nucleotide-binding protein G(olf) subunit alpha-like.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2-like.	0.763
GNB4	GNAL	ENSSSAP00000005848	ENSSSAP00000111640	Guanine nucleotide-binding protein subunit beta-4.	Guanine nucleotide-binding protein G(olf) subunit alpha-like.	0.763
GNB4	HTR4	ENSSSAP00000005848	ENSSSAP00000009273	Guanine nucleotide-binding protein subunit beta-4.	5-hydroxytryptamine receptor 4-like isoform X1; Belongs to the G-protein coupled receptor 1 family.	0.622
GNB4	LOC106566693	ENSSSAP00000005848	ENSSSAP00000009349	Guanine nucleotide-binding protein subunit beta-4.	Guanine nucleotide-binding protein G(S) subunit alpha-like.	0.763
GNB4	LOC106590334	ENSSSAP00000005848	ENSSSAP00000061889	Guanine nucleotide-binding protein subunit beta-4.	Guanine nucleotide-binding protein G(Olf) subunit alpha isoform X1.	0.763
GNB4	LOC106596458	ENSSSAP00000005848	ENSSSAP00000051674	Guanine nucleotide-binding protein subunit beta-4.	Guanine nucleotide-binding protein G(Olf) subunit alpha-like.	0.707
HTR4	ENSSSAP00000023970	ENSSSAP00000009273	ENSSSAP00000023970	5-hydroxytryptamine receptor 4-like isoform X1; Belongs to the G-protein coupled receptor 1 family.	5-hydroxytryptamine (serotonin) receptor 3A.	0.633
HTR4	GNAL	ENSSSAP00000009273	ENSSSAP00000111640	5-hydroxytryptamine receptor 4-like isoform X1; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein G(olf) subunit alpha-like.	0.855
HTR4	GNB4	ENSSSAP00000009273	ENSSSAP00000005848	5-hydroxytryptamine receptor 4-like isoform X1; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit beta-4.	0.622
HTR4	LOC106566693	ENSSSAP00000009273	ENSSSAP00000009349	5-hydroxytryptamine receptor 4-like isoform X1; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein G(S) subunit alpha-like.	0.855
HTR4	LOC106567725	ENSSSAP00000009273	ENSSSAP00000073907	5-hydroxytryptamine receptor 4-like isoform X1; Belongs to the G-protein coupled receptor 1 family.	5-hydroxytryptamine receptor 3A-like; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.633
HTR4	LOC106567879	ENSSSAP00000009273	ENSSSAP00000034767	5-hydroxytryptamine receptor 4-like isoform X1; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2-like.	0.622
HTR4	LOC106590334	ENSSSAP00000009273	ENSSSAP00000061889	5-hydroxytryptamine receptor 4-like isoform X1; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein G(Olf) subunit alpha isoform X1.	0.855
HTR4	LOC106596458	ENSSSAP00000009273	ENSSSAP00000051674	5-hydroxytryptamine receptor 4-like isoform X1; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein G(Olf) subunit alpha-like.	0.791
HTR4	slc27a4	ENSSSAP00000009273	ENSSSAP00000020958	5-hydroxytryptamine receptor 4-like isoform X1; Belongs to the G-protein coupled receptor 1 family.	Long-chain fatty acid transport protein 4.	0.641