Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
dis3l2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily. (1049 aa)    
Predicted Functional Partners:
exosc1
Exosome complex component CSL4 isoform X1.
   
 0.984
exosc10
Exosome component 10.
   
 0.980
exosc7
Exosome complex exonuclease RRP42.
   
 0.979
exos4
Exosome complex exonuclease RRP41.
   
 0.978
exosc3
Exosome complex component RRP40.
   
 0.976
exosc6
Exosome complex exonuclease MTR3.
   
 0.975
exosc5
Exosome complex component RRP46 isoform X1.
   
 0.973
exosc8
Exosome complex component RRP43.
   
 0.972
LOC100380870
Superkiller viralicidic activity 2-like 2.
   
 0.971
LOC106568406
Superkiller viralicidic activity 2-like 2 isoform X1.
   
 0.971
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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