STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dis3l2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily. (1049 aa)    
Predicted Functional Partners:
exosc1
Exosome complex component CSL4 isoform X1.
   
 0.993
exosc10
Exosome component 10.
   
 0.993
exos4
Exosome complex exonuclease RRP41.
   
 0.992
exosc8
Exosome complex component RRP43.
   
 0.992
exosc3
Exosome complex component RRP40.
   
 0.992
exosc5
Exosome complex component RRP46 isoform X1.
   
 0.991
exosc7
Exosome complex exonuclease RRP42.
   
 0.990
exosc6
Exosome complex exonuclease MTR3.
   
 0.989
LOC106566956
Exosome complex component RRP4-like.
   
 0.981
exos2
Exosome complex exonuclease RRP4.
   
 0.981
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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