STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC106611426Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (324 aa)    
Predicted Functional Partners:
LOC106577931
Gamma-secretase subunit PEN-2.
    
 0.973
LOC106605614
Gamma-secretase subunit PEN-2-like.
    
 0.973
LOC106569378
Nicastrin-like isoform X1.
   
 0.972
NCSTN
Nicastrin.
   
 0.972
LOC106587925
Gamma-secretase subunit Aph-1b-like.
   
 0.898
LOC106587972
Gamma-secretase subunit Aph-1b.
   
 0.898
LOC106571615
Gamma-secretase subunit Aph-1b-like.
   
 0.898
LOC106562852
Gamma-secretase subunit Aph-1b-like.
   
 0.898
LOC106574335
LOW QUALITY PROTEIN: amyloid beta A4 protein-like.
    
 
 0.844
LOC106586687
Amyloid beta A4 protein-like isoform X1.
    
 
 0.844
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.