Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ube2v1Ubiquitin-conjugating enzyme E2 variant 1. (157 aa)    
Predicted Functional Partners:
UBE2N
Ubiquitin-conjugating enzyme E2 N-like.
   
 0.959
LOC106576396
Ubiquitin-conjugating enzyme E2 N-like.
   
 0.959
ube2n
Ubiquitin-conjugating enzyme E2 N.
   
 0.959
LOC106562992
polyubiquitin-B.
   
 0.951
LOC106573305
Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.945
hltf
Helicase-like transcription factor.
    
 0.941
LOC100194654
Salmo salar ribosomal protein S27-3 (LOC100194654), mRNA.
   
 0.929
LOC106577118
ubiquitin-40S ribosomal protein S27a.
   
 0.929
polh
DNA polymerase eta.
    
 
 0.892
rnf8
E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]
   
 0.854
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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