STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC106603221Cornifelin homolog B-like. (114 aa)    
Predicted Functional Partners:
LOC106572481-2
Ubiquitin-conjugating enzyme E2 variant 1 isoform X2.
   
 0.979
LOC106572481
Ubiquitin-conjugating enzyme E2 variant 1 isoform X1.
   
 0.979
ENSSSAP00000041153
annotation not available
   
 0.979
LOC106612584
E3 ubiquitin-protein ligase TRIP12-like isoform X1.
   
 0.955
LOC106580884
E3 ubiquitin-protein ligase TRIP12 isoform X1.
   
 0.955
LOC106606575
Baculoviral IAP repeat-containing protein 6-like isoform X14.
   
 0.802
rnf8
E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]
   
 0.782
LOC106608776
E3 ubiquitin-protein ligase KEG-like.
    
 0.770
pex12
Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family.
    
 0.769
ZFAND4
AN1-type zinc finger protein 4-like.
   
 0.763
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.