Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC106569369E3 ubiquitin-protein ligase znrf1-like. (258 aa)    
Predicted Functional Partners:
LOC106562992
polyubiquitin-B.
   
  0.757
LOC106573305
Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.653
UBE2N
Ubiquitin-conjugating enzyme E2 N-like.
    
 
 0.653
LOC106576396
Ubiquitin-conjugating enzyme E2 N-like.
    
 
 0.653
ube2n
Ubiquitin-conjugating enzyme E2 N.
    
 
 0.653
LOC100194654
Salmo salar ribosomal protein S27-3 (LOC100194654), mRNA.
    
  0.554
LOC106577118
ubiquitin-40S ribosomal protein S27a.
    
  0.554
ATG7
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]
     
  0.552
allc
Probable allantoicase.
      
 0.550
aqr
Intron-binding protein aquarius.
      
 0.525
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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