Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSSSAP00000012484annotation not available (384 aa)    
Predicted Functional Partners:
babam1
BRISC and BRCA1-A complex member 1.
    
 0.724
brcc3
Lys-63-specific deubiquitinase BRCC36; Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not have activity toward 'Lys-48'-linked polyubiquitin chains. Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the brca1-bard1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). In the BRCA1-A complex, it specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX, antagonizing the rnf8-dependent ubiquitination at double- [...]
    
 0.645
LOC106603169
Lys-63-specific deubiquitinase BRCC36-like isoform X1.
    
 0.645
brca1
Breast cancer type 1 susceptibility protein isoform X2.
    
 0.644
babam2
BRCA1-A complex subunit BRE.
    
 0.613
ENSSSAP00000101354
annotation not available
    
 0.613
ENSSSAP00000064605
annotation not available
    
 0.515
LOC106582297
BRCA1-associated RING domain protein 1-like isoform X1.
    
 0.515
LOC106562992
polyubiquitin-B.
    
  0.487
LOC100194654
Salmo salar ribosomal protein S27-3 (LOC100194654), mRNA.
    
  0.457
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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