STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC106572411NEDD8-activating enzyme E1 catalytic subunit-like isoform X3. (137 aa)    
Predicted Functional Partners:
ula1
NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
   
 0.992
LOC106561978
NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
   
 0.992
ENSSSAP00000017711
annotation not available
   
 0.953
LOC106569431
NEDD8.
   
 0.953
LOC106577802
NEDD8-like.
   
 0.953
LOC106600265
NEDD8-like.
   
 0.953
ubc12
NEDD8-conjugating enzyme Ubc12; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.927
LOC106600804
NEDD8-conjugating enzyme Ubc12.
    
 0.927
ube2f
Salmo salar ubiquitin-conjugating enzyme E2F (putative) (ube2f), mRNA.
    
 0.927
LOC106582389
NEDD8-conjugating enzyme UBE2F-like; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.927
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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