STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC106599330PAX-interacting protein 1-like isoform X1. (1102 aa)    
Predicted Functional Partners:
LOC106562517
Tumor suppressor p53-binding protein 1-like isoform X3.
    
 0.952
ENSSSAP00000059858
annotation not available
    
 0.952
slf1
Ankyrin repeat domain-containing protein 32 isoform X1.
   
 0.950
atm
Non-specific serine/threonine protein kinase.
   
 0.941
ENSSSAP00000105257
Serine-protein kinase ATM-like.
   
 0.941
rnf8
E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]
    
 0.923
smc6
Structural maintenance of chromosomes protein 6 isoform X1.
   
 
 0.916
LOC106611344
Structural maintenance of chromosomes protein 6-like.
   
 
 0.916
brca1
Breast cancer type 1 susceptibility protein isoform X2.
   
 0.902
blm
Bloom syndrome protein isoform X1.
   
 
 0.901
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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