STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC106570038Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. (887 aa)    
Predicted Functional Partners:
LOC106611270
Endoribonuclease Dicer-like; Belongs to the helicase family. Dicer subfamily.
   
 0.905
LOC106602420
Endoribonuclease Dicer-like isoform X1; Belongs to the helicase family. Dicer subfamily.
   
 0.905
tarbp2
RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...]
    
 0.902
LOC106587198
Trinucleotide repeat-containing gene 6C protein-like isoform X1.
    
 0.896
LOC106564661
Trinucleotide repeat-containing gene 6C protein-like isoform X1.
    
 0.896
drosha
Ribonuclease 3 isoform X1.
   
 0.872
LOC106582463
Interferon-inducible double-stranded RNA-dependent protein kinase activator A homolog.
    
 0.853
LOC106586253
Interferon-inducible double-stranded RNA-dependent protein kinase activator A homolog.
    
 0.853
LOC106612565
39S ribosomal protein L44, mitochondrial-like.
   
 0.820
LOC106580952
39S ribosomal protein L44, mitochondrial-like.
   
 0.820
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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