STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tceancTranscription elongation factor A N-terminal and central domain-containing protein. (424 aa)    
Predicted Functional Partners:
polr2h
DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.
   
 0.934
RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2.
  
 0.920
twistnb
DNA-directed RNA polymerase I subunit RPA43.
   
 0.905
ENSSSAP00000040349
annotation not available
   
 0.902
gtf2e1
General transcription factor IIE subunit 1.
    
 0.885
LOC106569462
DNA-directed RNA polymerases I, II, and III subunit RPABC1.
   
 0.882
LOC106573578
DNA-directed RNA polymerases I, II, and III subunit RPABC1-like.
   
 0.882
med6
Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 0.881
LOC106601222
DNA-directed RNA polymerases I, II, and III subunit RPABC2.
   
 0.880
LOC106607142
DNA-directed RNA polymerases I, II, and III subunit RPABC2-like.
   
 0.880
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.