STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLCB1-21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1240 aa)    
Predicted Functional Partners:
LOC100196824
Inositol 1,4,5-trisphosphate receptor type 2 isoform X2.
   
 0.927
LOC106572092
Inositol 1,4,5-trisphosphate receptor type 3-like.
   
 0.927
LOC106565476
Inositol 1,4,5-trisphosphate receptor type 1 isoform X1.
   
 0.927
LOC106582863
Inositol 1,4,5-trisphosphate receptor type 1-like isoform X14.
   
 0.927
LOC106589429
Calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1.
   
 0.914
INPP5A
Type I inositol 1,4,5-trisphosphate 5-phosphatase-like isoform X1.
   
 
 0.913
LOC106595901
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
     
 0.912
PRKCA
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
     
 0.912
LOC100380658
Calcium/calmodulin-dependent protein kinase type II delta 1 chain isoform X1.
   
 
 0.910
LOC106565827
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
     
 0.909
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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