STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
brca1Breast cancer type 1 susceptibility protein isoform X2. (1567 aa)    
Predicted Functional Partners:
LOC106593073
Partner and localizer of BRCA2-like.
   
 0.999
babam1
BRISC and BRCA1-A complex member 1.
    
 0.999
brca2
Breast cancer type 2 susceptibility protein isoform X5.
   
 0.999
LOC106582297
BRCA1-associated RING domain protein 1-like isoform X1.
   
0.999
LOC106590210
DNA endonuclease RBBP8-like.
   
 0.999
atm
Non-specific serine/threonine protein kinase.
    
 0.997
brip1
Fanconi anemia group J protein.
   
 0.997
ENSSSAP00000064605
annotation not available
   
 0.997
MRE11
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
   
 0.995
Mre11
MRE11 homolog, double strand break repair nuclease.
   
 0.995
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.