Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC115171823Suppressor of cytokine signaling 3-like. (212 aa)    
Predicted Functional Partners:
LOC115192238
Leptin receptor-like.
    
 0.967
lepr
Leptin receptor.
    
 0.967
LOC115193942
Suppressor of cytokine signaling 5-like.
     
 0.962
LOC115199167
Non-receptor tyrosine-protein kinase TYK2-like.
    
 0.954
ENSSTUP00000038249
Tyrosine kinase 2.
    
 0.954
ENSSTUP00000009830
Janus kinase 2b.
    
 0.952
irs1
Insulin receptor substrate 1.
    
 0.945
LOC115159121
Tyrosine-protein kinase JAK2-like.
    
 0.944
ENSSTUP00000027422
Janus kinase 2a.
    
 0.944
LOC115192234
Tyrosine-protein kinase JAK1-like.
    
 0.944
Your Current Organism:
Salmo trutta
NCBI taxonomy Id: 8032
Other names: S. trutta, river trout
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