STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC115191708Cyclin-dependent kinase 4 inhibitor B-like. (126 aa)    
Predicted Functional Partners:
LOC115182075
E3 ubiquitin-protein ligase Mdm2-like.
  
 0.992
MDM2
MDM2 proto-oncogene.
  
 0.992
mdm4
MDM4 regulator of p53.
  
 0.984
LOC115198177
Cellular tumor antigen p53-like.
    
 0.977
LOC115154926
Cellular tumor antigen p53.
    
 0.977
LOC115194175
Cellular tumor antigen p53-like.
    
 0.977
CDK4
Cyclin-dependent kinase 4-like.
    
 0.959
LOC115207950
Cyclin-dependent kinase 4-like.
    
 0.959
CDK6
Cyclin-dependent kinase 6-like.
    
 0.951
LOC115175534
Cyclin-dependent kinase 6-like.
    
 0.951
Your Current Organism:
Salmo trutta
NCBI taxonomy Id: 8032
Other names: S. trutta, river trout
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.