Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Experiments
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[Homology]
Score
LOC115196032Mitogen-activated protein kinase kinase kinase 2-like. (638 aa)    
Predicted Functional Partners:
map2k5
Mitogen-activated protein kinase kinase 5.
    
 0.966
MAP2K5
Mitogen-activated protein kinase kinase 5.
    
 0.966
ENSSTUP00000044418
annotation not available
    
 0.927
map3k4
Mitogen-activated protein kinase kinase kinase 4.
    
 0.927
LOC115196222
Serine/threonine-protein kinase PAK 2-like.
    
 0.919
smyd3
SET and MYND domain containing 3.
    
 
 0.919
LOC115192529
Serine/threonine-protein kinase PAK 2.
    
 0.919
ENSSTUP00000074250
annotation not available
    
 0.919
pak2
P21 (RAC1) activated kinase 2.
    
 0.919
LOC115203637
TNF receptor-associated factor 6-like.
    
 0.909
Your Current Organism:
Salmo trutta
NCBI taxonomy Id: 8032
Other names: S. trutta, river trout
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