Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSSTUP00000012356Actin filament associated protein 1. (407 aa)    
Predicted Functional Partners:
ENSSTUP00000002783
GDP-mannose 4,6-dehydratase.
      
 0.642
LOC115200447
Growth arrest and DNA damage-inducible protein GADD45 gamma-like.
    
   0.642
LOC115164187
Growth arrest and DNA damage-inducible protein GADD45 gamma-like.
    
   0.642
tmco1
Transmembrane and coiled-coil domains 1.
      
 0.617
lrp12
LDL receptor related protein 12.
      
 0.600
txnrd2
Thioredoxin reductase 2.
      
 0.577
ENSSTUP00000114177
annotation not available
      
 0.577
ENSSTUP00000007693
annotation not available
     
 0.553
LOC115171446
Growth arrest-specific protein 7-like.
     
 0.553
LOC115201277
Growth arrest-specific protein 7-like.
     
 0.553
Your Current Organism:
Salmo trutta
NCBI taxonomy Id: 8032
Other names: S. trutta, river trout
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